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VPS18 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant VPS18.

  • WB - VPS18 Antibody (monoclonal) (M01) AT4519a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.52 KDa) .
  • WB - VPS18 Antibody (monoclonal) (M01) AT4519a
    VPS18 monoclonal antibody (M01), clone 4F8. Western Blot analysis of VPS18 expression in Raw 264.7 ( (Cat # AT4519a )
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9P253
Other Accession NM_020857
Reactivity Human, Mouse
Host mouse
Clonality Monoclonal
Isotype IgG3 Kappa
Clone Names 4F8
Calculated MW 110186 Da
Additional Information
Gene ID 57617
Other Names Vacuolar protein sorting-associated protein 18 homolog, hVPS18, VPS18, KIAA1475
Target/Specificity VPS18 (NP_065908, 3 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsVPS18 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps18 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway.


SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery. Zhu GD, et al. Mol Biol Cell, 2009 Feb. PMID 19109425.An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex. Xu L, et al. Mol Biol Cell, 2008 Dec. PMID 18799622.Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking. Liang C, et al. Nat Cell Biol, 2008 Jul. PMID 18552835.Large-scale mapping of human protein-protein interactions by mass spectrometry. Ewing RM, et al. Mol Syst Biol, 2007. PMID 17353931.Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Olsen JV, et al. Cell, 2006 Nov 3. PMID 17081983.

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$ 315.00
Cat# AT4519a
(40 western blots)
Availability: 7-10 days
Bulk Size
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