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VSNL1 Antibody (monoclonal) (M01)Purified Mouse Monoclonal Antibody (Mab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AT4523a | 100 ug 400 ul | 7-10 days | $ 315.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
VSNL1 Antibody (monoclonal) (M01) - Product info | |
| Application | WB
|
| Primary Accession | P62760 |
| Reactivity | Human |
| Isotype | IgG2a kappa |
| Clone Names | 2F1-E3 |
| Calculated MW | 22142 Da |
VSNL1 Antibody (monoclonal) (M01) - Additional info | |
| Gene ID 7447 | |
| Other Names HPCAL3, VILIPvisinin-like 1 | |
| Target/Specificity VSNL1 (AAH22012, 1 a.a. ~ 192 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| Dilution WB~~1:500~1000 | |
| Format Clear, colorless solution in phosphate buffered saline, pH 7.2 . | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions VSNL1 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures. | |
VSNL1 Antibody (monoclonal) (M01) - Related products
AP12201c: VSNL1 Antibody (Center)
AP1561a: VILIP1 Antibody (C-term)
RI15704: VSNL1 predesign siRNA
DC05168: Human VSNL1 cDNA Clone
LY11103a: VSNL1 Over-expression Lysate
VSNL1 Antibody (monoclonal) (M01) - Application data
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Western Blot analysis of VSNL1 expression in transfected 293T cell line by VSNL1 monoclonal antibody (M01), clone 2F1-E3.
Lane 1: VSNL1 transfected lysate(22.1 KDa).
Lane 2: Non-transfected lysate. -
Detection limit for recombinant GST tagged VSNL1 is approximately 0.3ng/ml as a capture antibody.
VSNL1 Antibody (monoclonal) (M01) - Research Areas
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BACKGROUND
This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
REFERENCES
MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia. Xu Y, et al. Schizophr Res, 2010 Jun. PMID 20347265.Visinin-like protein 1 regulates natriuretic peptide receptor B in the heart. Buttgereit J, et al. Regul Pept, 2010 Apr 9. PMID 20079378.Promoter regulation of the visinin-like subfamily of neuronal calcium sensor proteins by nuclear respiratory factor-1. Fu J, et al. J Biol Chem, 2009 Oct 2. PMID 19674972.Regulatory elements and functional implication for the formation of dimeric visinin-like protein-1. Chen KC, et al. J Pept Sci, 2009 Feb. PMID 19065602.Neuronal Ca2+ sensor VILIP-1 leads to the upregulation of functional alpha4beta2 nicotinic acetylcholine receptors in hippocampal neurons. Zhao CJ, et al. Mol Cell Neurosci, 2009 Feb. PMID 19063970.
