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WARS Antibody (monoclonal) (M02)Purified Mouse Monoclonal Antibody (Mab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AT4524a | 100 ug 400 ul | 7-10 days | $ 315.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
WARS Antibody (monoclonal) (M02) - Product info | |
| Application | IF, WB
|
| Primary Accession | P23381 |
| Other Accession | NP_004175 |
| Reactivity | Human |
| Concentration | 1 mg/ml |
| Isotype | IgG2a Kappa |
| Clone Names | 3A12 |
| Calculated MW | 53165 Da |
WARS Antibody (monoclonal) (M02) - Additional info | |
| Gene ID 7453 | |
| Other Names GAMMA2, IFI53, IFP53tryptophanyl-tRNA synthetase | |
| Target/Specificity WARS (NP_004175, 50 a.a. ~ 150 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| Dilution WB~~1:500~1000 | |
| Format Clear, colorless solution in phosphate buffered saline, pH 7.2 . | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions WARS Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. | |
WARS Antibody (monoclonal) (M02) - Related products
AP2934a: WARS Antibody (N-term)
WARS Antibody (monoclonal) (M02) - Application data
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Immunofluorescence of monoclonal antibody to WARS (AT4524a) on HeLa cell . [antibody concentration 10 ug/ml]
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WARS monoclonal antibody (M02), clone 3A12 Western Blot analysis of WARS expression in HeLa ( Cat # L013V1 ).
WARS Antibody (monoclonal) (M02) - Research Areas
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BACKGROUND
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene.
REFERENCES
Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.The prognostic significance of tryptophanyl-tRNA synthetase in colorectal cancer. Ghanipour A, et al. Cancer Epidemiol Biomarkers Prev, 2009 Nov. PMID 19900940.Allostery and conformational free energy changes in human tryptophanyl-tRNA synthetase from essential dynamics and structure networks. Bhattacharyya M, et al. Proteins, 2010 Feb 15. PMID 19768679.Increased TTS abrogates IDO-mediated CD4(+) T cells suppression in patients with Graves' disease. Wang S, et al. Endocrine, 2009 Aug. PMID 19363598.
