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WBSCR1 Antibody (monoclonal) (M07)

Mouse monoclonal antibody raised against a partial recombinant WBSCR1.

     
  • WB - WBSCR1 Antibody (monoclonal) (M07) AT4528a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
    detail
  • WB - WBSCR1 Antibody (monoclonal) (M07) AT4528a
    Western Blot analysis of WBSCR1 expression in transfected 293T cell line by WBSCR1 monoclonal antibody (M07), clone 4B2.

    Lane 1: WBSCR1 transfected lysate(27.4 KDa).
    Lane 2: Non-transfected lysate.
    detail
  • E - WBSCR1 Antibody (monoclonal) (M07) AT4528a
    Detection limit for recombinant GST tagged WBSCR1 is approximately 3ng/ml as a capture antibody.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q15056
Other Accession NM_031992
Reactivity Human
Host mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 4B2
Calculated MW 27385 Da
Additional Information
Gene ID 7458
Other Names Eukaryotic translation initiation factor 4H, eIF-4H, Williams-Beuren syndrome chromosomal region 1 protein, EIF4H, KIAA0038, WBSCR1, WSCR1
Target/Specificity WBSCR1 (NP_114381.1, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsWBSCR1 Antibody (monoclonal) (M07) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

This gene encodes one of the translation initiation factors, which functions to stimulate the initiation of protein synthesis at the level of mRNA utilization. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants.

References

Genome-wide searching of rare genetic variants in WTCCC data. Feng T, et al. Hum Genet, 2010 Sep. PMID 20549515.Detecting rare variants for complex traits using family and unrelated data. Zhu X, et al. Genet Epidemiol, 2010 Feb. PMID 19847924.Uncoupling stress granule assembly and translation initiation inhibition. Mokas S, et al. Mol Biol Cell, 2009 Jun. PMID 19369421.Topology and regulation of the human eIF4A/4G/4H helicase complex in translation initiation. Marintchev A, et al. Cell, 2009 Feb 6. PMID 19203580.Interactions between eIF4AI and its accessory factors eIF4B and eIF4H. Rozovsky N, et al. RNA, 2008 Oct. PMID 18719248.

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$ 350.00
Cat# AT4528a
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