WDR5 Antibody (monoclonal) (M01)
Mouse monoclonal antibody raised against a partial recombinant WDR5.
|Application ||WB, IF, E|
|Calculated MW||36588 Da|
|Other Names||WD repeat-containing protein 5, BMP2-induced 3-kb gene protein, WDR5, BIG3|
|Target/Specificity||WDR5 (NP_060058, 16 a.a. ~ 120 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||WDR5 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified.
A Three-Stage Genome-Wide Association Study of General Cognitive Ability: Hunting the Small Effects. Davis OS, et al. Behav Genet, 2010 Mar 21. PMID 20306291.PHF8 activates transcription of rRNA genes through H3K4me3 binding and H3K9me1/2 demethylation. Feng W, et al. Nat Struct Mol Biol, 2010 Apr. PMID 20208542.c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis. Jin S, et al. J Clin Invest, 2010 Feb 1. PMID 20093773.Regulation of HOXA2 gene expression by the ATP-dependent chromatin remodeling enzyme CHD8. Yates JA, et al. FEBS Lett, 2010 Feb 19. PMID 20085832.WDR5 is essential for assembly of the VISA-associated signaling complex and virus-triggered IRF3 and NF-kappaB activation. Wang YY, et al. Proc Natl Acad Sci U S A, 2010 Jan 12. PMID 20080758.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.