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YAP1 Antibody (monoclonal) (M03)
Mouse monoclonal antibody raised against a partial recombinant YAP1.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, IF, E |
|---|---|
| Primary Accession | P46937 |
| Other Accession | NM_006106 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 2H1 |
| Calculated MW | 54462 Da |
| Gene ID | 10413 |
|---|---|
| Other Names | Transcriptional coactivator YAP1, Yes-associated protein 1, Protein yorkie homolog, Yes-associated protein YAP65 homolog, YAP1, YAP65 |
| Target/Specificity | YAP1 (NP_006097, 53 a.a. ~ 161 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | YAP1 Antibody (monoclonal) (M03) is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes the human ortholog of chicken YAP protein which binds to the SH3 domain of the Yes proto-oncogene product. This protein contains a WW domain that is found in various structural, regulatory and signaling molecules in yeast, nematode, and mammals, and may be involved in protein-protein interaction.
References
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.MicroRNA-375 targets Hippo-signaling effector YAP in liver cancer and inhibits tumor properties. Liu AM, et al. Biochem Biophys Res Commun, 2010 Apr 9. PMID 20226166.Overexpression of yes-associated protein contributes to progression and poor prognosis of non-small-cell lung cancer. Wang Y, et al. Cancer Sci, 2010 May. PMID 20219076.Yap is a novel regulator of C2C12 myogenesis. Watt KI, et al. Biochem Biophys Res Commun, 2010 Mar 19. PMID 20153295.A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP). Zhao B, et al. Genes Dev, 2010 Jan 1. PMID 20048001.
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