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YY1 Antibody (monoclonal) (M02)Purified Mouse Monoclonal Antibody (Mab)
| Country | United States
Ordering Information
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|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| AT4563a | 100 ug 400 ul | 7-10 days | $ 315.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
YY1 Antibody (monoclonal) (M02) - Product info | |
| Application | IF, WB
|
| Primary Accession | P25490 |
| Other Accession | NP_003394 |
| Reactivity | Human |
| Isotype | IgG1 Kappa |
| Clone Names | 4A5 |
| Calculated MW | 44713 Da |
YY1 Antibody (monoclonal) (M02) - Additional info | |
| Gene ID 7528 | |
| Other Names DELTA, NFE1, UCRBP, YINYANG1YY1 transcription factor | |
| Target/Specificity YY1 (NP_003394, 221 a.a. ~ 321 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| Dilution WB~~1:500~1000 | |
| Format Clear, colorless solution in phosphate buffered saline, pH 7.2 . | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions YY1 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. | |
YY1 Antibody (monoclonal) (M02) - Related products
AP2517a: YY1 Antibody (N-term)
AP2517c: YY1 Antibody (Center)
BP2517a: YY1 Antibody (N-term) Blocking Peptide
BP2517c: YY1 Antibody (Center) Blocking Peptide
AT4562a: YY1 Antibody (monoclonal) (M01)
AT4563a: YY1 Antibody (monoclonal) (M02)
AT4564a: YY1 Antibody (monoclonal) (M03)
YY1 Antibody (monoclonal) (M02) - Application data
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Immunofluorescence of monoclonal antibody to YY1 (AT4563a) on HeLa cell . [antibody concentration 10 ug/ml]
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YY1 monoclonal antibody (M02), clone 4A5 Western Blot analysis of YY1 expression in Hela NE ( Cat # L013V3 ).
YY1 Antibody (monoclonal) (M02) - Research Areas
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BACKGROUND
YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.
REFERENCES
CXCR4/YY1 inhibition impairs VEGF network and angiogenesis during malignancy. de Nigris F, et al. Proc Natl Acad Sci U S A, 2010 Aug 10. PMID 20660740.Transcription factor YY1 interacts with retroviral integrases and facilitates integration of moloney murine leukemia virus cDNA into the host chromosomes. Inayoshi Y, et al. J Virol, 2010 Aug. PMID 20519390.Repressors NFI and NFY participate in organ-specific regulation of von Willebrand factor promoter activity in transgenic mice. Nassiri M, et al. Arterioscler Thromb Vasc Biol, 2010 Jul. PMID 20431063.Identification of Yin Yang 1-interacting partners at -1026C/A in the human iNOS promoter. Li W, et al. Arch Biochem Biophys, 2010 Jun 15. PMID 20430007.Identification of a Smad4/YY1-recognized and BMP2-responsive transcriptional regulatory module in the promoter of mouse GABA transporter subtype I (Gat1) gene. Yao M, et al. J Neurosci, 2010 Mar 17. PMID 20237276.