ZDHHC8 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a full length recombinant ZDHHC8.
|Calculated MW||81443 Da|
|Other Names||Probable palmitoyltransferase ZDHHC8, Zinc finger DHHC domain-containing protein 8, DHHC-8, Zinc finger protein 378, ZDHHC8, KIAA1292, ZDHHCL1, ZNF378|
|Target/Specificity||ZDHHC8 (AAH09442, 1 a.a. ~ 42 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||Clear, colorless solution in phosphate buffered saline, pH 7.2 .|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||ZDHHC8 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures.|
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This gene encodes a four transmembrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein may function as a palmitoyltransferase. Defects in this gene may be associated with a susceptibility to schizophrenia. Alternate splicing of this gene results in multiple transcript variants. A pseudogene of this gene is found on chromosome 22.
Testing for genetic association between the ZDHHC8 gene locus and susceptibility to schizophrenia: An integrated analysis of multiple datasets. Xu M, et al. Am J Med Genet B Neuropsychiatr Genet, 2010 May 24. PMID 20661937. Association of ZDHHC8 polymorphisms with smooth pursuit eye movement abnormality. Shin HD, et al. Am J Med Genet B Neuropsychiatr Genet, 2010 Sep. PMID 20468065. Association study of 182 candidate genes in anorexia nervosa. Pinheiro AP, et al. Am J Med Genet B Neuropsychiatr Genet, 2010 Jul. PMID 20468064. Proteome scale characterization of human S-acylated proteins in lipid raft-enriched and non-raft membranes. Yang W, et al. Mol Cell Proteomics, 2010 Jan. PMID 19801377. Palmitoylation of ATP-binding cassette transporter A1 is essential for its trafficking and function. Singaraja RR, et al. Circ Res, 2009 Jul 17. PMID 19556522.
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