|Other Accession||Q9H8V3, BC006838.1|
|Calculated MW||103505 Da|
|Other Names||Protein ECT2, Epithelial cell-transforming sequence 2 oncogene, ECT2|
|Target/Specificity||ECT2 (AAH06838.1, 46 a.a. ~ 145 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.|
|Format||In 1x PBS, pH 7.4|
|Storage||Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.|
|Precautions||ECT2 monoclonal antibody (M01) is for research use only and not for use in diagnostic or therapeutic procedures.|
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The protein encoded by this gene is a guanine nucleotide exchange factor and transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis. Several transcript variants encoding two different isoforms have been found for this gene.
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