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In Vivo Ready™ Anti-Mouse CD2 (RM2-5) Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, FA |
|---|---|
| Isotype | Rat IgG2b, lambda |
| Concentration | 2.0 mg/mL |
| Reactivity | Mouse |
| Formulation | 10 mM NaH2PO4, 150 mM NaCl, pH7.2 |
| Host | Rat |
| Gene ID | 12481 |
|---|---|
| Gene Name | Cd2 |
| Alternative Name(s) | LFA-2, Ly-37 |
| Format | In Vivo Ready™ |
| Storage Conditions | 2-8°C |
Provided below are standard protocols that you may find useful for product applications.
Background
The RM2-5 antibody reacts with mouse CD2, an approximately 50 kDa glycoprotein, and a member of the Ig superfamily. CD2, also known as LFA-2, is a receptor for CD48 in the mouse and is expressed on the cell surface of all lymphocytes. CD2 mediates cell to cell adhesion and is involved in T cell activation. RM2-5 is reported to block CD2-mediated cell:cell adhesion. Please choose the appropriate format for each application.
References
Yagita H, Nakamura T, Karasuyama H, Okumura K. 1989. Proc. Natl. Acad. Sci. 86(2):645-9.
Nakamura T, Takahashi K, Fukazawa T, Koyanagi M, Yokoyama A, Kato H, Yagita H, Okumura K. 1990. J. Immunol. 145(11):3628-34.
Criado G, Feito MJ, Rojo JM. 1996. Eur. J. Immunol. 26(6):1228-34.
Cibotti R, Punt JA, Dash KS, Sharrow SO, Singer A. 1997. Immunity. 6(3):245-55.
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