|Application ||IHC, ICC|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||132357 Da|
|Application & Usage||This anti-peptide antibody mixture was validated by immunohistochemistry (at a concentration of 3 µg/ml) using fluorescein-labeled goat anti-chicken IgY (1:500 dilution) as the secondary reagent.|
|Other Names||Metabotropic glutamate receptor 1, mGluR1, GRM1, GPRC1A, MGLUR1|
|Format||Mixture of IgY fraction (10 mg/ml) and affinity-purified antibodies (50 ug/ml) in Phosphate-buffered (10 mM) isotonic (0.9%, w/v) saline (PBS, pH 7.2) with sodium azide (0.02%, w/v).|
|Reconstitution & Storage||-20°C|
|Precautions||Glutamate Receptor (Metabotropic) Type 1 (mGluR1) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Detected in brain.|
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