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Glutamate Receptor (Metabotropic) Type 5 (mGluR5) Antibody

Purified Chicken Polyclonal Antibody

  • IF - Glutamate Receptor (Metabotropic) Type 5 (mGluR5) Antibody AVS10012
    Glutamate Receptor (Metabotropic) Type 5 (mGluR5)

    mGluR5-staining of pyramidal and granule cell neurons in the hippocampal formation of an adult transgenic mouse brain (red staining); Green staining is GFP-immunoreactivity under the control of a constitutive actin promoter.

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P41594
Reactivity Human, Mouse, Rat
Host Chicken
Calculated MW 132469 Da
Additional Information
Gene ID 2915
Application & Usage This anti-peptide antibody mixture was validated by immunohistochemistry (at a concentration of 3 µg/ml) using fluorescein-labeled goat anti-chicken IgY (1:500 dilution) as the secondary reagent.
Other Names Metabotropic glutamate receptor 5, mGluR5, GRM5, GPRC1E, MGLUR5
Format Mixture of IgY fraction (10 mg/ml) and affinity-purified antibodies (50 ug/ml) in Phosphate-buffered (10 mM) isotonic (0.9%, w/v) saline (PBS, pH 7.2) with sodium azide (0.02%, w/v).
Reconstitution & Storage -20°C
Background Descriptions
PrecautionsGlutamate Receptor (Metabotropic) Type 5 (mGluR5) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GRM5
Synonyms GPRC1E, MGLUR5
Function G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.
Cellular Location Cell membrane {ECO:0000269|PubMed:7908515, ECO:0000269|Ref.7}; Multi-pass membrane protein {ECO:0000269|PubMed:7908515, ECO:0000269|Ref.7}
Research Areas
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$ 335.00
Cat# AVS10012
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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