|Application ||WB, IHC, ICC|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||207124 Da|
|Application & Usage||Immunohistochemistry (at a concentration of 3 µg/ml) using fluorescein-labeled goat anti-chicken IgY (1:500 dilution, Aves Labs Cat. #F-1004) as the secondary reagent.|
|Other Names||Nestin, Nes|
|Format||Mixture of IgY fraction (10 mg/ml) and affinity-purified antibodies (50 ug/ml) in Phosphate-buffered (10 mM) isotonic (0.9%, w/v) saline (PBS, pH 7.2) with sodium azide (0.02%, w/v).|
|Reconstitution & Storage||-20°C|
|Precautions||Nestin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division (By similarity). Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.|
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