|Application ||IHC, ICC|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||33873 Da|
|Application & Usage||Immunohistochemistry (1:1000 dilution) using 2% paraformaldehyde-fixed tissues.|
|Other Names||RNA binding protein fox-1 homolog 3, Fox-1 homolog C, RBFOX3|
|Format||Mixture of IgY fraction (10 mg/ml) and affinity-purified antibodies (50 ug/ml) in Phosphate-buffered (10 mM) isotonic saline (0.9%, w.v) saline (PBS, pH 7.2) with 50% (v/v) glycerol and sodium azide (0.02%, w/v).|
|Reconstitution & Storage||-20°C|
|Precautions||Neu-N (Fox 3) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD).|
|Cellular Location||Nucleus. Cytoplasm. Note=Largely restricted to neuronal nuclei. However, significant cytoplasmic localization in neurons from brains from HIV-infected individuals with cognitive impairment.|
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