|Application ||IHC, ICC|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||43717 Da|
|Other Names||Prostatic acid phosphatase, 220.127.116.11, 5'-nucleotidase, 5'-NT, 18.104.22.168, Ecto-5'-nucleotidase, Fluoride-resistant acid phosphatase, FRAP, Thiamine monophosphatase, TMPase, Acpp|
|Format||10 mg/ml of chicken total IgY antibody supplemented with 20 µg/ml of affinity purified antibody. The vehicle is phosphate-buffered isotonic saline (PBS) (50% by volume) and glycerol (50% by volume) supplemented with 0.02% sodium azide as a preservative.|
|Reconstitution & Storage||-20°C|
|Precautions||Prostatic Acid Phosphatase (PAP) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma (By similarity).|
|Cellular Location||Isoform 1: Secreted|
|Tissue Location||Isoform 1 is expressed in salivary gland, thymus and thyroid gland. Isoform 2 is widely expressed in prostate lobes, brain, kidney, liver, lung, muscle, placenta, salivary gland, spleen, thyroid and thymus. Locates to Schwann cells and fibroblasts. Expressed in peptidergic and non- peptidergic nociceptive (pain-sensing) neurons. Preferentially expressed in non-peptidergic doral root ganglia neurons|
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