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Integrin alpha-M (CD11b, MAC-1, OX-42 Antigen) Antibody

Purified Chicken Polyclonal Antibody

     
  • IF - Integrin alpha-M (CD11b, MAC-1, OX-42 Antigen) Antibody AVS10035
    Mac-1 staining of the microglial cells in mouse cerebral cortex (red). Photo courtesy of Dr. Felix Eckenstein, University of Vermont.
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC, ICC
Primary Accession P11215
Reactivity Human, Mouse, Rat
Host Chicken
Calculated MW 127179 Da
Additional Information
Gene ID 3684
Application & Usage Immunohistochemistry (at a concentration of 100 ug/ml) using HRP-labeled goat anti-chicken IgY (1:1000 dilution) as the secondary reagent. Please note that these dilutions are meant to serve as starting points, and that optimal dilutions may vary
Other Names Integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, CD11b, ITGAM, CD11B, CR3A
Format Phosphate-buffered (10 mM) isotonic saline (0.9%, w.v) with sodium azide (0.02%, w/v) added as a preservative.
Reconstitution & Storage -20°C
Background Descriptions
PrecautionsIntegrin alpha-M (CD11b, MAC-1, OX-42 Antigen) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ITGAM
Synonyms CD11B, CR3A
Function Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Predominantly expressed in monocytes and granulocytes
Research Areas
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$ 335.00
Cat# AVS10035
Size:
Quantity:
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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