|Application ||WB, IHC-P|
|Calculated MW||H=39 KDa|
|Antigen Region||1-326 aa|
|Other Names||ANXA1;ANX1; LPC1; Annexin A1; Annexin A1; Annexin I; Annexin A1; Annexin-1; Annexin A1; Calpactin II; Annexin A1; Calpactin-2; Annexin A1; Chromobindin-9; Annexin A1; Lipocortin I; Annexin A1; Phospholipase A2 inhibitory protein; Annexin A1; p35|
|Target/Specificity||Purified His-tagged ANXA1 protein was used to produced this monoclonal antibody.|
|Format||Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ANXA1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity.|
|Cellular Location||Nucleus. Cytoplasm. Cell projection, cilium. Basolateral cell membrane. Note=Found in the cilium, nucleus and basolateral cell membrane of ciliated cells in the tracheal endothelium. Found in the cytoplasm of type II pneumocytes and alveolar macrophages.|
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Provided below are standard protocols that you may find useful for product applications.
Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity.
Wallner B.P., et al. Nature 320:77-81(1986).
Kovacic R.T., et al. Biochemistry 30:9015-9021(1991).
Arcone R., et al. Eur. J. Biochem. 211:347-355(1993).
Varticovski L., et al. Biochemistry 27:3682-3690(1988).
Biemann K., et al. Science 237:992-998(1987).
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