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HMGA2 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - HMGA2 Antibody (N-term) AW5342-U100
    Western blot analysis of lysates from HepG2,NCCIT,mouse NIH/3T3 cell line (from left to right), using HMGA2 Antibody (N-term)(Cat. #AW5342). AW5342 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.Lysates at 20ug per lane.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P52926
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW H=12, 9, 10, 11;M=12 KDa
Isotype Rabbit IgG
Antigen Source HUMAN
Additional Information
Gene ID 8091
Antigen Region 15-49 aa
Other Names High mobility group protein HMGI-C, High mobility group AT-hook protein 2, HMGA2, HMGIC
Dilution WB~~1:1000
Target/Specificity This HMGA2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 15-49 amino acids from the N-terminal region of human HMGA2.
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHMGA2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HMGA2
Synonyms HMGIC
Function Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Plays a role in postnatal myogenesis, is involved in satellite cell activation (By similarity). Positively regulates IGF2 expression through PLAG1 and in a PLAG1-independent manner (PubMed:28796236).
Cellular Location Nucleus.
Research Areas
Citations (0)
citation

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Background

Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes.

References

Patel U.A.,et al.Biochem. Biophys. Res. Commun. 201:63-70(1994).
Schoenmakers E.F.P.M.,et al.Nat. Genet. 10:436-444(1995).
Chau K.-Y.,et al.Nucleic Acids Res. 23:4262-4266(1995).
Ashar H.R.,et al.Genomics 31:207-214(1996).
Hauke S.,et al.Biochim. Biophys. Acta 1729:24-31(2005).

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$ 370.00
Cat# AW5342-U100
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