|Calculated MW||H=60,45;M=60;R=60 KDa|
|Antigen Region||465-499 aa|
|Other Names||Amine oxidase [flavin-containing] A, Monoamine oxidase type A, MAO-A, MAOA|
|Target/Specificity||This MAOA antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 465-499 amino acids from the C-terminal region of human MAOA.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MAOA Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine.|
|Cellular Location||Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side|
|Tissue Location||Heart, liver, duodenum, blood vessels and kidney|
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Provided below are standard protocols that you may find useful for product applications.
Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine.
Hsu Y.-P.P.,et al.J. Neurochem. 51:1321-1324(1988).
Bach A.W.J.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:4934-4938(1988).
Chen Z.-Y.,et al.Nucleic Acids Res. 19:4537-4541(1991).
Grimsby J.,et al.Proc. Natl. Acad. Sci. U.S.A. 88:3637-3641(1991).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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