|Reactivity||Human, Mouse, Rat|
|Calculated MW||H=41;M=41;R=41 KDa|
|Antigen Region||157-185 aa|
|Other Names||Hydroxyacid oxidase 1, HAOX1, Glycolate oxidase, GOX, HAO1, GOX1, HAOX1|
|Target/Specificity||This HAO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-185 amino acids from the Central region of human HAO1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||HAO1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2- hydroxy octanoate.|
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Provided below are standard protocols that you may find useful for product applications.
HAO1 is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids.
Jones,J.M., et.al., J. Biol. Chem. 275 (17), 12590-12597 (2000)
Kohler,S.A., et.al., J. Biol. Chem. 274 (4), 2401-2407 (1999)
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