|Reactivity||Human, Mouse, Rat, Hamster|
|Calculated MW||H=68;M=68 KDa|
|Antigen Region||597-631 aa|
|Other Names||Acetylcholinesterase, AChE, ACHE|
|Target/Specificity||This ACHE antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 597-631 amino acids from the C-terminal region of human ACHE.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ACHE Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.|
|Cellular Location||Cell junction, synapse Secreted. Cell membrane; Peripheral membrane protein Isoform H: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side|
|Tissue Location||Isoform H is highly expressed in erythrocytes.|
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Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.
Soreq H.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:9688-9692(1990).
Karpel R.,et al.Exp. Cell Res. 210:268-277(1994).
Yang L.,et al.Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Totoki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
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