|Calculated MW||M=63 KDa|
|Antigen Region||532-558 aa|
|Other Names||Glucose-6-phosphate isomerase, GPI, Autocrine motility factor, AMF, Neuroleukin, NLK, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI, Gpi, Gpi1|
|Target/Specificity||This Mouse Gpi antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 532-558 amino acids from the C-terminal region of mouse Gpi.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Gpi Antibody(C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons.|
|Cellular Location||Cytoplasm. Secreted.|
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Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons.
Benveniste, P., et al. Cell Stem Cell 6(1):48-58(2010)
Repiso, A., et al. Anat Histol Embryol 37(5):380-382(2008)
Szuber, N., et al. Exp. Hematol. 36(7):773-785(2008)
Chandele, A., et al. J. Immunol. 180(8):5309-5319(2008)
Cuda, C.M., et al. J. Immunol. 179(11):7439-7447(2007)
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