|Calculated MW||H=39 KDa|
|Antigen Region||142-169 aa|
|Other Names||Vacuolar protein sorting-associated protein 37C, hVps37C, ESCRT-I complex subunit VPS37C, VPS37C, PML39|
|Target/Specificity||This VPS37C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 142-169 amino acids from the Central region of human VPS37C.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||VPS37C Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.|
|Cellular Location||Late endosome membrane; Peripheral membrane protein. Note=Probably associates with membranes. Recruited to the plasma membrane by HIV-1|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
VPS37C is a subunit of ESCRT-I (endosomal sorting complex required for transport I), a complex in the class E vacuolar protein sorting (VPS) pathway required for sorting ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies (Eastman et al., 2005 [PubMed 15509564]).
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)
Eastman, S.W., et al. J. Biol. Chem. 280(1):628-636(2005)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.