|Reactivity||Human, Mouse, Rat|
|Calculated MW||H=42;M=42;R=42 KDa|
|Antigen Region||70-96 aa|
|Other Names||Glutamine synthetase, GS, Glutamate decarboxylase, Glutamate--ammonia ligase, GLUL, GLNS|
|Target/Specificity||This GLUL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-96 amino acids from the N-terminal region of human GLUL.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GLUL Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner (By similarity). Essential for proliferation of fetal skin fibroblasts.|
|Cellular Location||Cytoplasm. Mitochondrion.|
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Provided below are standard protocols that you may find useful for product applications.
GLUL belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling.
Di Tommaso,L., et.al., J. Hepatol. 50 (4), 746-754 (2009)
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