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SLC5A4 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - SLC5A4 Antibody (C-term) AW5571-U100
    All lanes : Anti-SLC5A4 Antibody (C-term) at 1:1000 dilution Lane 1: human liver lysate Lane 2: human spleen lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 72 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9NY91
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW H=72 KDa
Isotype Rabbit IgG
Antigen Source HUMAN
Additional Information
Gene ID 6527
Antigen Region 601-635 aa
Other Names Low affinity sodium-glucose cotransporter, Sodium/glucose cotransporter 3, Na(+)/glucose cotransporter 3, Solute carrier family 5 member 4, SLC5A4, SAAT1, SGLT2
Dilution WB~~1:1000
Target/Specificity This SLC5A4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 601-635 amino acids from the C-terminal region of human SLC5A4.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSLC5A4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC5A4 {ECO:0000303|PubMed:13130073}
Function Does not function as sodium/D-glucose symporter (PubMed:13130073, PubMed:20421923, PubMed:22766068). However, may function as a D-glucose sensor by generating a D-glucose-induced depolarization which is pH-independent, Na(+)-dependent at neutral pH and probably H(+)-dependent at acidic pH (PubMed:13130073, PubMed:22766068, PubMed:17110502, PubMed:20421923).
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Expressed in skeletal muscle, where it may localize to the neuromuscular junction (at protein level) (PubMed:13130073) Expressed in small intestine where it may localize to cholinergic neurons of the submucosal plexus and myenteric plexus (at protein level) (PubMed:13130073). Detected in kidney (at protein level) (PubMed:22766068).
Research Areas
Citations (0)
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Background

Sodium-dependent glucose transporter.

References

Gorboulev V.,et al.Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
Dunham I.,et al.Nature 402:489-495(1999).
Poppe R.,et al.Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases.

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$ 370.00
Cat# AW5571-U100
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