|Calculated MW||H=30;M=29;R=30 KDa|
|Antigen Region||95-121 aa|
|Other Names||Peflin, PEF protein with a long N-terminal hydrophobic domain, Penta-EF hand domain-containing protein 1, PEF1, ABP32|
|Target/Specificity||This PEF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-121 amino acids from the Central region of human PEF1.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PEF1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Cytoplasm. Membrane; Peripheral membrane protein. Note=Membrane-associated in the presence of Ca(2+)|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. The encoded protein has been shown to form a heterodimer with the programmed cell death 6 gene product and may modulate its function in Ca(2+) signaling. Alternative splicing results in multiple transcript variants and a pseudogene has been identified on chromosome 1.
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Hansen, C., et al. FEBS Lett. 545 (2-3), 151-154 (2003) :
Satoh, H., et al. Biochim. Biophys. Acta 1600 (1-2), 61-67 (2002) :
Kitaura, Y., et al. Arch. Biochem. Biophys. 399(1):12-18(2002)
Kitaura, Y., et al. J. Biol. Chem. 276(17):14053-14058(2001)
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