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ETV1 Antibody (C-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - ETV1 Antibody (C-Term) AW5611-U100
    All lanes : Anti-ETV1 Antibody (C-Term) at 1:2000 dilution Lane 1: human brain lysate Lane 2: Hela whole cell lysate Lane 3: HT-29 whole cell lysate Lane 4: mouse heart lysate Lane 5: mouse kidney lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 55 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P50549
Other Accession Q2KIC2, P41164
Reactivity Human, Mouse
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW H=55,53,52,43,48,50;M=55 KDa
Isotype Rabbit IgG
Antigen Source HUMAN
Additional Information
Gene ID 2115
Antigen Region 434-465 aa
Other Names ETS translocation variant 1, Ets-related protein 81, ETV1, ER81
Dilution WB~~0.25
Target/Specificity This ETV1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 434-465 amino acids from human ETV1.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsETV1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ETV1 (HGNC:3490)
Function Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3' (PubMed:7651741). Required for olfactory dopaminergic neuron differentiation; may directly activate expression of tyrosine hydroxylase (TH) (By similarity).
Cellular Location Nucleus {ECO:0000255|PROSITE-ProRule:PRU00237}.
Tissue Location Very highly expressed in brain, highly expressed in testis, lung and heart, moderately in spleen, small intestine, pancreas and colon, weakly in liver, prostate and thymus, very weakly in skeletal muscle, kidney and ovary and not in placenta and peripheral blood leukocytes.
Research Areas
Citations (0)
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Background

Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'.

References

Jeon I.-S.,et al.Oncogene 10:1229-1234(1995).
Monte D.,et al.Oncogene 11:771-779(1995).
Coutte L.,et al.Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.

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$ 370.00
Cat# AW5611-U100
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