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DANRE arnt2 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - DANRE arnt2 Antibody (Center) Azb10020a
    DANRE arnt2 Antibody (Center) (Cat. #Azb10020a) western blot analysis in zebra fish brain tissue lysates (35ug/lane).This demonstrates the ARNT2 antibody detected the ARNT2 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9DG12
Reactivity Zebrafish
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 80972 Da
Antigen Region 475-501 aa
Additional Information
Gene ID 64277
Other Names Aryl hydrocarbon receptor nuclear translocator 2, ARNT protein 2, zfARNT2, arnt2 {ECO:0000312|ZFIN:ZDB-GENE-001207-3}
Target/Specificity This DANRE arnt2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 475-501 amino acids from the Central region of DANRE arnt2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDANRE arnt2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name arnt2 {ECO:0000312|ZFIN:ZDB-GENE-001207-3}
Function Transcription factor that plays a role in the development of the hypothalamo-pituitary axis. Specifically recognizes the xenobiotic response element (XRE) (By similarity). Isoform 1 acts as a transcriptional activator (PubMed:11072074). Isoform 3 acts as a transcriptional repressor (PubMed:10960127, PubMed:11072074).
Cellular Location Nucleus.
Tissue Location Isoform 1 and isoform 2 are most highly expressed in the brain, eye and skeletal muscle and to a lower degree in liver, heart, kidney and swim bladder. Isoform 3 is most highly expressed in the eye, forebrain, midbrain, hindbrain, skeletal muscle, gills and brain but is barely detectable in liver, heart, kidney and swim bladder. Before the pharyngula period isoform 3 is expressed throughout the entire embryo and during this period extensively in the brain and eye.
Research Areas
Citations (0)
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Background

Specifically recognizes the xenobiotic response element (XRE). Isoform 1 acts as a transcriptional activator. Isoform 3 acts as a transcriptional repressor.

References

Tanguay R.L., et al. Biochim. Biophys. Acta 1494:117-128(2000).
Wang W.-D., et al. Mar. Biotechnol. 2:376-386(2000).

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$ 365.00
$ 140.00
Cat# Azb10020a
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