|Application ||WB, E|
|Calculated MW||105529 Da|
|Antigen Region||691-717 aa|
|Other Names||Protein HEG, Heart of glass, heg|
|Target/Specificity||This DANRE heg antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 691-717 amino acids from the C-terminal region of DANRE heg.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DANRE heg Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions.|
|Cellular Location||Isoform 1: Cell membrane; Single-pass type I membrane protein. Cell junction Isoform 3: Secreted.|
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Provided below are standard protocols that you may find useful for product applications.
Receptor component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions.
Mably J.D., et al. Curr. Biol. 13:2138-2147(2003).
Kleaveland B., et al. Nat. Med. 15:169-176(2009).
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