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DANRE hey2 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - DANRE hey2 Antibody (C-term) Azb10024b
    DANRE hey2 Antibody (C-term) (Cat. #Azb10024b) western blot analysis in zebra fish brain tissue lysates (35ug/lane).This demonstrates the DANRE hey2 antibody detected the DANRE hey2 protein (arrow).
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9I9L0
Reactivity Zebrafish
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 34329 Da
Antigen Region 295-322 aa
Additional Information
Gene ID 58146
Other Names Hairy/enhancer-of-split related with YRPW motif protein 2, Protein gridlock, hey2, grl
Target/Specificity This DANRE hey2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 295-322 amino acids from the C-terminal region of DANRE hey2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDANRE hey2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name hey2
Synonyms grl
Function Transcriptional repressor (By similarity). Downstream effector of Notch signaling which regulates cell fate choice in angioblasts. Represses the venous cell fate, thereby promoting the arterial cell fate and aorta formation.
Cellular Location Nucleus {ECO:0000255|PROSITE-ProRule:PRU00380, ECO:0000255|PROSITE-ProRule:PRU00981}
Research Areas
Citations (0)
citation

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Background

Transcriptional repressor (By similarity). Downstream effector of Notch signaling which regulates cell fate choice in angioblasts. Represses the venous cell fate, thereby promoting the arterial cell fate and aorta formation.

References

Zhong T.P., et al. Science 287:1820-1824(2000).
Zhong T.P., et al. Nature 414:216-220(2001).
Winkler C., et al. Dev. Genes Evol. 213:541-553(2003).

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$ 365.00
$ 140.00
Cat# Azb10024b
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