|Application ||WB, E|
|Calculated MW||58765 Da|
|Antigen Region||332-364 aa|
|Other Names||Amine oxidase [flavin-containing], Monoamine oxidase, MAO, Z-MAO, AOF|
|Target/Specificity||This DANRE mao antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 332-364 amino acids from the Central region of DANRE mao.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DANRE mao Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. Oxidizes both 5-hydroxytryptamine (5-HT) and beta-phenylethylamine (PEA).|
|Cellular Location||Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side|
|Tissue Location||Strongest expression in brain and intestine, followed by liver, heart and gill. Little expression in spleen, eye or muscle. In brain, highest activity in noradrenergic and serotonergic cell groups and those of the habenulointerpeduncular pathway; moderate levels in dopaminergic cell clusters|
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Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. Oxidizes both 5-hydroxytryptamine (5-HT) and beta-phenylethylamine (PEA).
Setini A., et al. Comp. Biochem. Physiol. 140B:153-161(2005).
Anichtchik O., et al. J. Comp. Neurol. 498:593-610(2006).
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