|Application ||WB, E|
|Other Accession||Q6ZWS8, O43791, Q0VCW1, Q0IHH9, Q7ZX06, Q9VFP2|
|Predicted||Drosophila, Xenopus, Bovine, Human|
|Calculated MW||42134 Da|
|Other Names||Speckle-type POZ protein, HIB homolog 1, SPOP1, spop|
|Target/Specificity||This (DANRE) spop antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 74-107 amino acids from the N-terminal region of human (DANRE) spop.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||(DANRE) spop Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation.|
|Cellular Location||Nucleus. Nucleus speckle|
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Provided below are standard protocols that you may find useful for product applications.
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation (By similarity).
Zhang Q.,et al.Dev. Cell 10:719-729(2006).
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