|Application ||WB, E|
|Other Accession||P49187, Q61831, P53779, P49186, Q9WTU6, P45984, P79996, Q8QHK8, P49185, Q91Y86, P45983, P92208, Q8WQG9|
|Predicted||C.Elegans, Drosophila, Human, Mouse, Rat, Xenopus, Chicken|
|Calculated MW||44140 Da|
|Other Names||Mitogen-activated protein kinase 8, MAP kinase 8, MAPK 8, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1, mapk8, jnk1|
|Target/Specificity||This DANRE mapk8 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 183-215 amino acids from the human region of DANRE mapk8.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||(DANRE) mapk8 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Responds to activation by environmental stress and pro- inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. May play a role in the regulation of the circadian clock.|
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Responds to activation by environmental stress and pro- inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity (By similarity).
Fujii R.,et al.J. Cell Biol. 150:1335-1348(2000).
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