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LOC552889 Antibody (Center) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q96GX2
Other Accession NP_001129734.1
Clone Names 100107065
Additional Information
Gene ID 552889
Other Names Putative ataxin-7-like protein 3B, ATXN7L3B
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ATXN7L3B
Function By binding to ENY2, interferes with the nuclear functions of the deubiquitinase (DUB) module of the SAGA complex which consists of ENY2, ATXN7, ATXN7L3 and the histone deubiquitinating component USP22. Affects USP22 DUB activity toward histones indirectly by changing the subcellular distribution of ENY2 and altering ENY2 availability for ATXN7L3 interaction. Regulates H2B monoubiquitination (H2Bub1) levels through cytoplasmic sequestration of ENY2 resulting in loss of nuclear ENY2-ATXN7L3 association which destabilizes ATXN7L3. Affects protein expression levels of ENY2 and ATXN7L3.
Cellular Location Cytoplasm.
Research Areas
Citations (0)
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$ 277.78
Cat# BP10056c
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