|Other Accession||P50440, NP_001473.1, NP_878904.2, NP_065693.2|
|Other Names||A-kinase-interacting protein 1, Breast cancer-associated gene 3 protein, PKA-interacting protein, Proline-rich protein BCA3, AKIP1, BCA3, C11orf17|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRKACA. Regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade.|
|Cellular Location||Nucleus. Note=Locates to punctate spots|
|Tissue Location||Expressed at high levels in adult heart and at lower levels in brain, testis, ovary and skeletal muscle. Up- regulated in some breast cancer cell lines. Isoform 1 and isoform 3 are expressed in fetal brain.|
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Provided below are standard protocols that you may find useful for product applications.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Gao, N., et al. J. Biol. Chem. 285(36):28097-28104(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Gao, N., et al. J. Biol. Chem. 283(12):7834-7843(2008)Lamesch, P., et al. Genomics 89(3):307-315(2007)
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