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AEBP1 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8IUX7 |
|---|---|
| Other Accession | NP_001120.3 |
| Clone Names | 80305116 |
| Gene ID | 165 |
|---|---|
| Other Names | Adipocyte enhancer-binding protein 1, AE-binding protein 1, Aortic carboxypeptidase-like protein, AEBP1, ACLP |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | AEBP1 |
|---|---|
| Synonyms | ACLP |
| Function | [Isoform 1]: As a positive regulator of collagen fibrillogenesis, it is probably involved in the organization and remodeling of the extracellular matrix. |
| Cellular Location | [Isoform 1]: Secreted {ECO:0000250|UniProtKB:Q640N1} |
| Tissue Location | Expressed in osteoblast and visceral fat. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The adipocyte enhancer binding protein 1 is atranscriptional repressor with carboxypeptidase (CP) activity. Thisprotein binds to a regulatory sequence, adipocyte enhancer 1(AE-1), located in the proximal promoter region of the adipose P2(aP2) gene, which encodes the adipocyte fatty-acid binding protein.It is characterized as a member of the regulatory B-like CP family.This protein seems to be activated by a novel mechanism, wherebythe direct binding of DNA enhances its protease activity.Adipocyte-enhancer binding protein 1 may play a role indifferentiated vascular smooth muscle cells.
References
Majdalawieh, A., et al. Nucl Recept Signal 8, E004 (2010) :Schissel, S.L., et al. Am. J. Pathol. 174(3):818-828(2009)Zhang, L., et al. Mol. Med. 11 (1-12), 39-47 (2005) :Layne, M.D., et al. Mol. Cell. Biol. 21(15):5256-5261(2001)Muise, A.M., et al. Biochem. J. 343 PT 2, 341-345 (1999) :
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