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AEBP1 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q8IUX7
Other Accession NP_001120.3
Clone Names 80305116
Peptide ID 80305116
Additional Information
Gene ID 165
Other Names Adipocyte enhancer-binding protein 1, AE-binding protein 1, Aortic carboxypeptidase-like protein, AEBP1, ACLP
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name AEBP1
Synonyms ACLP
Function May positively regulate MAP-kinase activity in adipocytes, leading to enhanced adipocyte proliferation and reduced adipocyte differentiation. May also positively regulate NF-kappa-B activity in macrophages by promoting the phosphorylation and subsequent degradation of I-kappa-B-alpha (NFKBIA), leading to enhanced macrophage inflammatory responsiveness. Can act as a transcriptional repressor.
Cellular Location Isoform 1: Secreted {ECO:0000250|UniProtKB:Q640N1}
Tissue Location Expressed in osteoblast and visceral fat.
Research Areas
Citations (0)

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The adipocyte enhancer binding protein 1 is atranscriptional repressor with carboxypeptidase (CP) activity. Thisprotein binds to a regulatory sequence, adipocyte enhancer 1(AE-1), located in the proximal promoter region of the adipose P2(aP2) gene, which encodes the adipocyte fatty-acid binding protein.It is characterized as a member of the regulatory B-like CP family.This protein seems to be activated by a novel mechanism, wherebythe direct binding of DNA enhances its protease activity.Adipocyte-enhancer binding protein 1 may play a role indifferentiated vascular smooth muscle cells.


Majdalawieh, A., et al. Nucl Recept Signal 8, E004 (2010) :Schissel, S.L., et al. Am. J. Pathol. 174(3):818-828(2009)Zhang, L., et al. Mol. Med. 11 (1-12), 39-47 (2005) :Layne, M.D., et al. Mol. Cell. Biol. 21(15):5256-5261(2001)Muise, A.M., et al. Biochem. J. 343 PT 2, 341-345 (1999) :

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$ 80.00
Cat# BP10098c
Availability: In Stock
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