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AMD1 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P17707 |
|---|---|
| Other Accession | NP_001625.2 |
| Clone Names | 80311191 |
| Gene ID | 262 |
|---|---|
| Other Names | S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC, S-adenosylmethionine decarboxylase alpha chain, S-adenosylmethionine decarboxylase beta chain, AMD1, AMD |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | AMD1 |
|---|---|
| Synonyms | AMD |
| Function | Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes an important intermediate enzyme inpolyamine biosynthesis. The polyamines spermine, spermidine, andputrescine are low-molecular-weight aliphatic amines essential forcellular proliferation and tumor promotion. Two alternativelyspliced transcript variants that encode different proteins havebeen identified. Pseudogenes of this gene are found on chromosomes5, 6, 10, X and Y.
References
Levine, A.J., et al. Cancer Epidemiol. Biomarkers Prev. 19(7):1812-1821(2010)Reynolds, R., et al. Invest. Ophthalmol. Vis. Sci. 50(12):5818-5827(2009)Bale, S., et al. Biochemistry 48(27):6423-6430(2009)Franke, B., et al. Birth Defects Res. Part A Clin. Mol. Teratol. 85(3):216-226(2009)Bale, S., et al. Biochemistry 47(50):13404-13417(2008)
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