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ANGPTL1 Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession O95841
Other Accession NP_004664.1
Clone Names 80411110
Peptide ID 80411110
Additional Information
Other Names Angiopoietin-related protein 1, Angiopoietin-3, ANG-3, Angiopoietin-like protein 1, ANGPTL1, ANG3, ANGPT3, ARP1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ANGPTL1
Synonyms ANG3, ANGPT3, ARP1
Cellular Location Secreted.
Tissue Location Highly expressed in adrenal gland, placenta, thyroid gland, heart, skeletal muscle and small intestine. Weakly expressed in testis, ovary, colon, pancreas, kidney and stomach EMBL; AF107253; AAD19608.1; -; mRNA EMBL; AY358278; AAQ88645.1; -; mRNA EMBL; AB056476; BAB40691.1; -; mRNA EMBL; AL355520; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; BC050640; AAH50640.1; -; mRNA CCDS; CCDS1327.1; - RefSeq; NP_004664.1; NM_004673.3 RefSeq; XP_005245634.1; XM_005245577.2 UniGene; Hs.591474; - ProteinModelPortal; O95841; - SMR; O95841; - STRING; 9606.ENSP00000234816; - iPTMnet; O95841; - PhosphoSitePlus; O95841; - BioMuta; ANGPTL1; - EPD; O95841; - PaxDb; O95841; - PeptideAtlas; O95841; - PRIDE; O95841; - ProteomicsDB; 51085; - Ensembl; ENST00000234816; ENSP00000234816; ENSG00000116194 Ensembl; ENST00000367629; ENSP00000356601; ENSG00000116194 GeneID; 9068; - KEGG; hsa:9068; - UCSC; uc001gma.4; human CTD; 9068; - DisGeNET; 9068; - EuPathDB; HostDB:ENSG00000116194.12; - GeneCards; ANGPTL1; - HGNC; HGNC:489; ANGPTL1 HPA; HPA009976; - MIM; 603874; gene neXtProt; NX_O95841; - OpenTargets; ENSG00000116194; - PharmGKB; PA24794; - eggNOG; KOG2579; Eukaryota eggNOG; ENOG410ZYS4; LUCA GeneTree; ENSGT00920000148944; - HOGENOM; HOG000037129; - HOVERGEN; HBG103336; - InParanoid; O95841; - OMA; QLWCENS; - OrthoDB; EOG091G03M1; - PhylomeDB; O95841; - TreeFam; TF336658; - SignaLink; O95841; - SIGNOR; O95841; - GeneWiki; ANGPTL1; - GenomeRNAi; 9068; - PRO; PR:O95841; - Proteomes; UP000005640; Chromosome 1 Bgee; ENSG00000116194; - CleanEx; HS_ANGPTL1; - ExpressionAtlas; O95841; baseline and differential Genevisible; O95841; HS GO; GO:0070062; C:extracellular exosome; HDA:UniProtKB GO; GO:0005615; C:extracellular space; IDA:MGI GO; GO:0005102; F:signaling receptor binding; TAS:ProtInc GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:Ensembl CDD; cd00087; FReD; 1 InterPro; IPR036056; Fibrinogen-like_C InterPro; IPR002181; Fibrinogen_a/b/g_C_dom InterPro; IPR020837; Fibrinogen_CS Pfam; PF00147; Fibrinogen_C; 1 SMART; SM00186; FBG; 1 SUPFAM; SSF56496; SSF56496; 1 PROSITE; PS00514; FIBRINOGEN_C_1; 1 PROSITE; PS51406; FIBRINOGEN_C_2; 1 2: Evidence at transcript level; Coiled coil; Complete proteome; Disulfide bond; Glycoprotein; Reference proteome; Secreted; Signal SIGNAL 1 23 CHAIN 24 491 Angiopoietin-related protein 1 /FTId=PRO_0000009118 DOMAIN 271 491 Fibrinogen C-terminal {ECO:0000255|PROSITE-ProRule:PRU00739} COILED 80 168 CARBOHYD 160 160 N-linked (GlcNAc...) asparagine CARBOHYD 188 188 N-linked (GlcNAc...) asparagine DISULFID 280 309 {ECO:0000255|PROSITE-ProRule:PRU00739} DISULFID 432 445 {ECO:0000255|PROSITE-ProRule:PRU00739} SEQUENCE 491 AA; 56720 MW; 3C4DB8DEF6CF7E99 CRC64; MKTFTWTLGV LFFLLVDTGH CRGGQFKIKK INQRRYPRAT DGKEEAKKCA YTFLVPEQRI TGPICVNTKG QDASTIKDMI TRMDLENLKD VLSRQKREID VLQLVVDVDG NIVNEVKLLR KESRNMNSRV TQLYMQLLHE IIRKRDNSLE LSQLENKILN VTTEMLKMAT RYRELEVKYA SLTDLVNNQS VMITLLEEQC LRIFSRQDTH VSPPLVQVVP QHIPNSQQYT PGLLGGNEIQ RDPGYPRDLM PPPDLATSPT KSPFKIPPVT FINEGPFKDC QQAKEAGHSV SGIYMIKPEN SNGPMQLWCE NSLDPGGWTV IQKRTDGSVN FFRNWENYKK GFGNIDGEYW LGLENIYMLS NQDNYKLLIE LEDWSDKKVY AEYSSFRLEP ESEFYRLRLG TYQGNAGDSM MWHNGKQFTT LDRDKDMYAG NCAHFHKGGW WYNACAHSNL NGVWYRGGHY RSKHQDGIFW AEYRGGSYSL RAVQMMIKPI D
Research Areas
Citations (0)

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Background

Angiopoietins are members of the vascular endothelialgrowth factor family and the only known growth factors largelyspecific for vascular endothelium. Angiopoietin-1, angiopoietin-2,and angiopoietin-4 participate in the formation of blood vessels.The protein encoded by this gene is another member of theangiopoietin family that is widely expressed in adult tissues withmRNA levels highest in highly vascularized tissues. This proteinwas found to be a secretory protein that does not act as anendothelial cell mitogen in vitro.

References

Di Carlo, C., et al. Fertil. Steril. 91(6):2315-2323(2009)Post, S., et al. J. Vasc. Res. 45(3):244-250(2008)Dhanabal, M., et al. Biochem. Biophys. Res. Commun. 333(2):308-315(2005)Smagur, A., et al. Acta Biochim. Pol. 52(4):875-879(2005)Lee, H.J., et al. FASEB J. 18(11):1200-1208(2004)

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$ 80.00
Cat# BP10105a
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