|Other Accession||NP_958850.1, NP_001725.1|
|Other Names||Complement C1s subcomponent, C1 esterase, Complement component 1 subcomponent s, Complement C1s subcomponent heavy chain, Complement C1s subcomponent light chain, C1S|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a serine protease, which is a majorconstituent of the human complement subcomponent C1. C1s associateswith two other complement components C1r and C1q in order to yieldthe first component of the serum complement system. Defects in thisgene are the cause of selective C1s deficiency. [provided byRefSeq].
Han, S., et al. Hum. Immunol. 71(7):727-730(2010)Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)Pflieger, D., et al. Mol. Cell Proteomics 9(4):593-610(2010)Cerhan, J.R., et al. Br. J. Haematol. 145(5):614-623(2009)Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 18(5):1651-1658(2009)
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