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AEN Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8WTP8 |
|---|---|
| Other Accession | NP_073604.3 |
| Clone Names | 80808001 |
| Gene ID | 64782 |
|---|---|
| Other Names | Apoptosis-enhancing nuclease, 31--, Interferon-stimulated 20 kDa exonuclease-like 1, AEN, ISG20L1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | AEN |
|---|---|
| Synonyms | ISG20L1 |
| Function | Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single- stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis. |
| Cellular Location | Nucleus. Nucleus, nucleolus. Note=Localized predomintly in the nucleolus. Translocates from the nucleolus to the nucleoplasm upon apoptosis induction |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Eby, K.G., et al. Mol. Cancer 9, 95 (2010) :Kawase, T., et al. Oncogene 27(27):3797-3810(2008)Lamesch, P., et al. Genomics 89(3):307-315(2007)Lee, J.H., et al. Biochem. Biophys. Res. Commun. 337(1):39-47(2005)
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