ABLIM1 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O14639 |
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Other Accession | NP_002304.3, NP_006711.3, NP_001003407.1, NP_001003408.1 |
Clone Names | 80924026 |
Gene ID | 3983 |
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Other Names | Actin-binding LIM protein 1, abLIM-1, Actin-binding LIM protein family member 1, Actin-binding double zinc finger protein, LIMAB1, Limatin, ABLIM1, ABLIM, KIAA0059, LIMAB1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ABLIM1 |
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Synonyms | ABLIM, KIAA0059, LIMAB1 |
Function | May act as scaffold protein (By similarity). May play a role in the development of the retina. Has been suggested to play a role in axon guidance. |
Cellular Location | Cytoplasm. Cytoplasm, cytoskeleton. Note=Associated with the cytoskeleton. |
Tissue Location | Detected in liver, heart, skeletal muscle, brain and retina, where it is concentrated in the inner segment and in the outer plexiform layers. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a cytoskeletal LIM protein that binds toactin filaments via a domain that is homologous to erythrocytedematin. LIM domains, found in over 60 proteins, play key roles inthe regulation of developmental pathways. LIM domains also functionas protein-binding interfaces, mediating specific protein-proteininteractions. The protein encoded by this gene could mediate suchinteractions between actin filaments and cytoplasmic targets.Alternatively spliced transcript variants encoding differentisoforms have been identified.
References
Feng, T., et al. Hum. Genet. 128(3):269-280(2010)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Matsuoka, S., et al. Science 316(5828):1160-1166(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)
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