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ADAM22 Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9P0K1
Other Accession NP_068369.1, NP_004185.1, NP_057435.2, NP_068367.1, NP_068368.2
Clone Names 80924040
Peptide ID 80924040
Additional Information
Gene ID 53616
Other Names Disintegrin and metalloproteinase domain-containing protein 22, ADAM 22, Metalloproteinase-disintegrin ADAM22-3, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2, ADAM22, MDC2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADAM22
Synonyms MDC2
Function Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein (PubMed:19692335). Involved in regulation of cell adhesion and spreading and in inhibition of cell proliferation. Neuronal receptor for LGI1.
Cellular Location Membrane; Single-pass type I membrane protein. Cell projection, axon {ECO:0000250|UniProtKB:Q9R1V6}
Tissue Location Highly expressed in the brain and in some high-grade but not low-grade gliomas. Detected slightly or not at all in other tissues.
Research Areas
Citations (0)

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This gene encodes a member of the ADAM (a disintegrin andmetalloprotease domain) family. Members of this family aremembrane-anchored proteins structurally related to snake venomdisintegrins, and have been implicated in a variety of biologicalprocesses involving cell-cell and cell-matrix interactions,including fertilization, muscle development, and neurogenesis. Thisgene is highly expressed in the brain and may function as anintegrin ligand in the brain. Alternative splicing results inseveral transcript variants.


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Sagane, K., et al. J. Recept. Signal Transduct. Res. 30(2):72-77(2010)Ozkaynak, E., et al. J. Neurosci. 30(10):3857-3864(2010)Gregorio, S.P., et al. Psychiatry Res 165 (1-2), 1-9 (2009) :Sorensen, H.P., et al. Protein Expr. Purif. 61(2):175-183(2008)

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$ 80.00
Cat# BP10118a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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