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ASCC1 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8N9N2 |
|---|---|
| Other Accession | NP_057031.2 |
| Clone Names | 80924070 |
| Gene ID | 51008 |
|---|---|
| Other Names | Activating signal cointegrator 1 complex subunit 1, ASC-1 complex subunit p50, Trip4 complex subunit p50, ASCC1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ASCC1 |
|---|---|
| Function | Plays a role in DNA damage repair as component of the ASCC complex (PubMed:29997253). Part of the ASC-1 complex that enhances NF- kappa-B, SRF and AP1 transactivation (PubMed:12077347). In cells responding to gastrin-activated paracrine signals, it is involved in the induction of SERPINB2 expression by gastrin. May also play a role in the development of neuromuscular junction. |
| Cellular Location | Nucleus. Nucleus speckle. Note=Colocalizes with PRPF8 in nuclear speckles in the absence of DNA damage. |
| Tissue Location | Ubiquitous.. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Almeida-Vega, S., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 296 (2), G414-G423 (2009) :Halaschek-Wiener, J., et al. PLoS ONE 4 (8), E6641 (2009) :Lamesch, P., et al. Genomics 89(3):307-315(2007)Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)Jung, D.J., et al. Mol. Cell. Biol. 22(14):5203-5211(2002)
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