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ADH4 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession P08319
Other Accession NP_000661.2
Clone Names 90429009
Additional Information
Gene ID 127
Other Names Alcohol dehydrogenase 4, Alcohol dehydrogenase class II pi chain, ADH4
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADH4 (HGNC:252)
Function Catalyzes the NAD-dependent oxidation of either all-trans- retinol or 9-cis-retinol (PubMed:17279314). Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate (PubMed:16081420). Also catalyzes the reduction of benzoquinones (PubMed:10514444).
Cellular Location Cytoplasm.
Research Areas
Citations (0)
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Background

This gene encodes class II alcohol dehydrogenase 4 pisubunit, which is a member of the alcohol dehydrogenase family.Members of this enzyme family metabolize a wide variety ofsubstrates, including ethanol, retinol, other aliphatic alcohols,hydroxysteroids, and lipid peroxidation products. Class II alcoholdehydrogenase is a homodimer composed of 2 pi subunits. It exhibitsa high activity for oxidation of long-chain aliphatic alcohols andaromatic alcohols and is less sensitive to pyrazole. This gene islocalized to chromosome 4 in the cluster of alcohol dehydrogenasegenes.

References

Pochareddy, S., et al. Gene 460 (1-2), 1-7 (2010) :Preuss, U.W., et al. Addict Biol (2010) In press :Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)Rainero, I., et al. Headache 50(1):92-98(2010)Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :

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$ 277.78
Cat# BP10128b
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