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CCL21 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O00585
Other Accession NP_002980.1
Clone Names 90713029
Peptide ID 90713029
Additional Information
Gene ID 6366
Other Names C-C motif chemokine 21, 6Ckine, Beta-chemokine exodus-2, Secondary lymphoid-tissue chemokine, SLC, Small-inducible cytokine A21, CCL21, SCYA21
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CCL21
Synonyms SCYA21
Function Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Cellular Location Secreted.
Tissue Location Highly expressed in high endothelial venules of lymph nodes, spleen and appendix. Intermediate levels found in small intestine, thyroid gland and trachea. Low level expression in thymus, bone marrow, liver, and pancreas. Also found in tonsil, fetal heart and fetal spleen
Research Areas
Citations (0)

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This gene is one of several CC cytokine genes clustered onthe p-arm of chromosome 9. Cytokines are a family of secretedproteins involved in immunoregulatory and inflammatory processes.The CC cytokines are proteins characterized by two adjacentcysteines. Similar to other chemokines the protein encoded by thisgene inhibits hemopoiesis and stimulates chemotaxis. This proteinis chemotactic in vitro for thymocytes and activated T cells, butnot for B cells, macrophages, or neutrophils. The cytokine encodedby this gene may also play a role in mediating homing oflymphocytes to secondary lymphoid organs. It is a high affinityfunctional ligand for chemokine receptor 7 (CCR7) that is expressedon T and B lymphocytes and a known receptor for another member ofthe cytokine family (small inducible cytokine A19). [provided byRefSeq].


Rey-Gallardo, A., et al. Glycobiology 20(9):1139-1146(2010)Cuesta-Mateos, C., et al. Exp. Hematol. 38(9):756-764(2010)Sundqvist, J., et al. Fertil. Steril. (2010) In press :Plant, D., et al. Ann. Rheum. Dis. 69(8):1548-1553(2010)Farragher, T.M., et al. Arthritis Care Res (Hoboken) 62(5):676-682(2010)

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$ 80.00
Cat# BP10134c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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