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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   CCNY Antibody (Center) Blocking peptide   

CCNY Antibody (Center) Blocking peptide

Synthetic peptide

     
  • SPECIFICATION
  • CITATIONS
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Product Information
Primary Accession Q8ND76
Other Accession NP_659449.3, NP_859049.2
Clone Names 90713032
Peptide ID 90713032
Additional Information
Gene ID 219771
Other Names Cyclin-Y, Cyc-Y, Cyclin box protein 1, Cyclin fold protein 1, cyclin-X, CCNY, C10orf9, CBCP1, CFP1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CCNY
Synonyms C10orf9, CBCP1, CFP1
Function Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription.
Cellular Location Cell membrane; Lipid-anchor; Cytoplasmic side
Tissue Location Widely expressed.
Research Areas
Citations (0)

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Background

Cyclins, such as CCNY, control cell division cycles andregulate cyclin-dependent kinases (e.g., CDC2; MIM 116940) (Li etal., 2009 [PubMed 18060517]).

References

Wang, K., et al. Hum. Mol. Genet. 19(10):2059-2067(2010)Xu, Y., et al. Oncol. Res. 18(8):359-364(2010)Chapuis, J., et al. Mol. Psychiatry 14(11):1004-1016(2009)Henckaerts, L., et al. Clin. Gastroenterol. Hepatol. 7(9):972-980(2009)Jiang, M., et al. FEBS Lett. 583(13):2171-2178(2009)

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$ 80.00
Cat# BP10135c
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