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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   TNFRSF6B Antibody (N-term) Blocking peptide   

TNFRSF6B Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O95407
Other Accession NP_116563.1, NP_003814.1
Clone Names 90713237
Peptide ID 90713237
Additional Information
Gene ID 8771
Other Names Tumor necrosis factor receptor superfamily member 6B, Decoy receptor 3, DcR3, Decoy receptor for Fas ligand, M68, TNFRSF6B, DCR3, TR6
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms DCR3, TR6
Function Decoy receptor that can neutralize the cytotoxic ligands TNFS14/LIGHT, TNFSF15 and TNFSF6/FASL. Protects against apoptosis.
Cellular Location Secreted.
Tissue Location Detected in fetal lung, brain and liver. Detected in adult stomach, spinal cord, lymph node, trachea, spleen, colon and lung. Highly expressed in several primary tumors from colon, stomach, rectum, esophagus and in SW480 colon carcinoma cells
Research Areas
Citations (0)

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This gene belongs to the tumor necrosis factor receptorsuperfamily. The encoded protein is postulated to play a regulatoryrole in suppressing FasL- and LIGHT-mediated cell death. It acts asa decoy receptor that competes with death receptors for ligandbinding. Overexpression of this gene has been noted ingastrointestinal tract tumors, and it is located in a gene-richcluster on chromosome 20, with other potentially tumor-relatedgenes. Two transcript variants encoding the same isoform, butdiffering in the 5' UTR, have been observed for this gene.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Xiong, G., et al. Tumour Biol. 31(5):443-449(2010)Sung, H.Y., et al. Int. J. Radiat. Biol. 86(9):780-790(2010)Brunetti, G., et al. Ann. N. Y. Acad. Sci. 1192, 298-302 (2010) :Perdigones, N., et al. Arthritis Rheum. 62(3):705-710(2010)

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$ 80.00
Cat# BP10136a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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