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ABCC3 Antibody (Center) Blocking peptideSynthetic peptide
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| BP10144c | 0.1 mg 400 ul | In Stock | $ 45.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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- Backgrounds
ABCC3 Antibody (Center) Blocking peptide - Product info | |
| Primary Accession | O15438 |
| Other Accession | NP_003777.2, NP_001137542.1 |
| Clone Names | 90819014 |
| Calculated MW | 169343 Da |
ABCC3 Antibody (Center) Blocking peptide - Additional info | |
| Gene ID 8714 | |
| Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
ABCC3 Antibody (Center) Blocking peptide - Protein Information | |
| Name ABCC3 | |
| Synonyms CMOAT2, MLP2, MRP3 | |
| Function May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes (By similarity) | |
| Cellular Location Membrane; Multi-pass membrane protein. | |
| Tissue Location Mainly expressed in the liver. Also expressed in small intestine, colon, prostate, testis, brain and at a lower level in the kidney | |
ABCC3 Antibody (Center) Blocking peptide - Related products
ABCC3 Antibody (Center) Blocking peptide - Research Areas
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BACKGROUND
The protein encoded by this gene is a member of thesuperfamily of ATP-binding cassette (ABC) transporters. ABCproteins transport various molecules across extra- andintra-cellular membranes. ABC genes are divided into seven distinctsubfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). Thisprotein is a member of the MRP subfamily which is involved inmulti-drug resistance. The specific function of this protein hasnot yet been determined; however, this protein may play a role inthe transport of biliary and intestinal excretion of organicanions. Alternatively spliced variants which encode differentprotein isoforms have been described; however, not all variantshave been fully characterized.
REFERENCES
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Hoffman, A.D., et al. Protein J. 29(5):373-379(2010)Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Moyer, A.M., et al. Cancer Epidemiol. Biomarkers Prev. 19(3):811-821(2010)
