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TIMP4 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q99727
Other Accession NP_003247.1
Clone Names 90805116
Peptide ID 90805116
Additional Information
Gene ID 7079
Other Names Metalloproteinase inhibitor 4, Tissue inhibitor of metalloproteinases 4, TIMP-4, TIMP4
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TIMP4
Function Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP- 9.
Cellular Location Secreted.
Tissue Location Abundant in heart and present at low levels in many other tissues
Research Areas
Citations (0)

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This gene belongs to the TIMP gene family. The proteinsencoded by this gene family are inhibitors of the matrixmetalloproteinases, a group of peptidases involved in degradationof the extracellular matrix. The secreted, netrin domain-containingprotein encoded by this gene is involved in regulation of plateletaggregation and recruitment and may play role in hormonalregulation and endometrial tissue remodeling.


Nalpas, B., et al. Gut 59(8):1120-1126(2010)Bailey, S.D., et al. Diabetes Care (2010) In press :Wojciechowski, R., et al. Invest. Ophthalmol. Vis. Sci. (2010) In press :Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Liss, M., et al. Am. J. Pathol. 175(3):940-946(2009)

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$ 80.00
Cat# BP10148c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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