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FCN2 Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q15485
Other Accession NP_004099.2, NP_056652.1
Clone Names 90805033
Additional Information
Gene ID 2220
Other Names Ficolin-2, 37 kDa elastin-binding protein, Collagen/fibrinogen domain-containing protein 2, EBP-37, Ficolin-B, Ficolin-beta, Hucolin, L-ficolin, Serum lectin p35, FCN2, FCNL
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name FCN2
Synonyms FCNL
Function May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin. Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region.
Cellular Location Secreted.
Tissue Location Expressed by the liver and secreted in plasma.
Research Areas
Citations (0)
citation

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Background

The product of this gene belongs to the ficolin family ofproteins. This family is characterized by the presence of a leaderpeptide, a short N-terminal segment, followed by a collagen-likeregion, and a C-terminal fibrinogen-like domain. This gene ispredominantly expressed in the liver, and has been shown to havecarbohydrate binding and opsonic activities. Alternatively splicedtranscript variants encoding different isoforms have beenidentified.

References

de Rooij, B.J., et al. Hepatology 52(3):1100-1110(2010)Meijvis, S.C., et al. Nephrol. Dial. Transplant. (2010) In press :Davila, S., et al. Genes Immun. 11(3):232-238(2010)Cedzynski, M., et al. Mol. Immunol. 47 (2-3), 415-419 (2009) :Liu, J., et al. Cell. Mol. Immunol. 6(4):235-244(2009)

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$ 277.78
Cat# BP10149a
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